Extended Stay Hotels in Florence, SC

22 Extended Stay hotels near Florence, SC

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Suburban Studios Florence - Darlington
1914 West Lucas Street, I-95 & US 52,
Florence, SC, 29501, US
2.84 mi from Florence, SC
2.9 stars rating. 1313 reviews2.9 stars rating. 1313 reviews
Save 6%
Strikethrough Rate:~~$46~~Discounted rate:$43USD/night
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MainStay Suites
1819 West Lucas Street, Building B,
Florence, SC, 29501, US
2.79 mi from Florence, SC
1.8 stars rating. 47 reviews1.8 stars rating. 47 reviews
Save 6%
Strikethrough Rate:~~$68~~Discounted rate:$64USD/night
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Below are additional hotels in the area that do not match your exact search criteria.

Econo Lodge
1920 West Lucas Street,
Florence, SC, 29501, US
2.86 mi from Florence, SC
2.9 stars rating. 1334 reviews2.9 stars rating. 1334 reviews
Save 25%
Strikethrough Rate:~~$62~~Discounted rate:$47USD/night
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Sleep Inn Florence North
1833 Florence Park Dr., I-95 & US 52,
Florence, SC, 29501, US
3.31 mi from Florence, SC
3.7 stars rating. 1916 reviews3.7 stars rating. 1916 reviews
Save 6%
Strikethrough Rate:~~$83~~Discounted rate:$78USD/night
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Comfort Suites Florence I-95
2120 West Lucas Street,
Florence, SC, 29501, US
3.32 mi from Florence, SC
4.3 stars rating. 2475 reviews4.3 stars rating. 2475 reviews
Save 24%
Strikethrough Rate:~~$143~~Discounted rate:$109USD/night
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Comfort Inn & Suites
527 Woody Jones Blvd.,
Florence, SC, 29501, US
3.9 mi from Florence, SC
4.5 stars rating. 1060 reviews4.5 stars rating. 1060 reviews
Save 5%
Strikethrough Rate:~~$146~~Discounted rate:$139USD/night
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Quality Inn & Suites Florence Civic Center
150 Dunbarton Drive,
Florence, SC, 29501, US
4.24 mi from Florence, SC
4 stars rating. 1662 reviews4 stars rating. 1662 reviews
Save 6%
Strikethrough Rate:~~$106~~Discounted rate:$99USD/night
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Quality Inn
903 South Fifth Street,
Hartsville, SC, 29550, US
20.61 mi from Florence, SC
3 stars rating. 379 reviews3 stars rating. 379 reviews
Save 6%
Strikethrough Rate:~~$70~~Discounted rate:$66USD/night
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Quality Inn Mullins - Marion
2693 E. Hwy. 76,
Mullins, SC, 29574-6009, US
24.29 mi from Florence, SC
3.7 stars rating. 534 reviews3.7 stars rating. 534 reviews
Save 6%
Strikethrough Rate:~~$108~~Discounted rate:$101USD/night
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Quality Inn & Suites
202 North Ron McNair Blvd.,
Lake City, SC, 29560, US
22.06 mi from Florence, SC
3.3 stars rating. 88 reviews3.3 stars rating. 88 reviews
Save 6%
Strikethrough Rate:~~$158~~Discounted rate:$148USD/night
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Econo Lodge Cheraw Market Street
820 Market St,
Cheraw, SC, 29520, US
34.91 mi from Florence, SC
4.4 stars rating. 31 reviews4.4 stars rating. 31 reviews
Save 6%
Strikethrough Rate:~~$85~~Discounted rate:$80USD/night
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Quality Inn Bennettsville
213 Hwy 15-401 Bypass East,
Bennettsville, SC, 29512, US
28.98 mi from Florence, SC
3.7 stars rating. 492 reviews3.7 stars rating. 492 reviews
Save 6%
Strikethrough Rate:~~$104~~Discounted rate:$98USD/night
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Quality Inn Cheraw
885 Chesterfield Highway,
Cheraw, SC, 29520, US
35.67 mi from Florence, SC
3.9 stars rating. 690 reviews3.9 stars rating. 690 reviews
Save 10%
Strikethrough Rate:~~$101~~Discounted rate:$91USD/night
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Quality Inn
1610 North Longstreet Street,
Kingstree, SC, 29556, US
35.71 mi from Florence, SC
2.7 stars rating. 186 reviews2.7 stars rating. 186 reviews
Save 6%
Strikethrough Rate:~~$92~~Discounted rate:$86USD/night
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Quality Inn Manning I-95
3031 Paxville Highway,
Manning, SC, 29102, US
43.74 mi from Florence, SC
4.1 stars rating. 86 reviews4.1 stars rating. 86 reviews
Save 6%
Strikethrough Rate:~~$97~~Discounted rate:$91USD/night
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Quality Inn
817 Radford Boulevard,
Dillon, SC, 29536, US
28.05 mi from Florence, SC
3.7 stars rating. 780 reviews3.7 stars rating. 780 reviews
Save 6%
Strikethrough Rate:~~$98~~Discounted rate:$91USD/night
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Econo Lodge
1101 Church Street Hwy 501,
Conway, SC, 29526, US
47.34 mi from Florence, SC
3.1 stars rating. 609 reviews3.1 stars rating. 609 reviews
Save 10%
Strikethrough Rate:~~$95~~Discounted rate:$86USD/night
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Sleep Inn
2510 Broad Street,
Sumter, SC, 29150, US
39.71 mi from Florence, SC
3.5 stars rating. 1359 reviews3.5 stars rating. 1359 reviews
Save 6%
Strikethrough Rate:~~$103~~Discounted rate:$96USD/night
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Quality Inn Conway Northwest
3345 W Highway 501,
Conway, SC, 29526, US
44.04 mi from Florence, SC
3.5 stars rating. 927 reviews3.5 stars rating. 927 reviews
Save 6%
Strikethrough Rate:~~$109~~Discounted rate:$102USD/night
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Comfort Inn
1699 US Highway 401 Bypass,
Laurinburg, NC, 28352, US
41.63 mi from Florence, SC
3.7 stars rating. 794 reviews3.7 stars rating. 794 reviews
Save 28%
Strikethrough Rate:~~$119~~Discounted rate:$86USD/night
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Comfort Inn & Suites
220 Wall Street,
Camden, SC, 29020, US
47.27 mi from Florence, SC
3.7 stars rating. 924 reviews3.7 stars rating. 924 reviews
Save 6%
Strikethrough Rate:~~$120~~Discounted rate:$112USD/night
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Comfort Suites
2500 Broad Street,
Sumter, SC, 29150-1851, US
39.64 mi from Florence, SC
3.7 stars rating. 1369 reviews3.7 stars rating. 1369 reviews
Save 10%
Strikethrough Rate:~~$163~~Discounted rate:$147USD/night
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Change your dates to book properties below.

Clarion Inn & Suites
1819 West Lucas Street, Building A,
Florence, SC, 29501, US
2.75 mi from Florence, SC
1.9 stars rating. 178 reviews1.9 stars rating. 178 reviews
Sold outfor your selected dates
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Country Inn & Suites by Radisson, Florence, SC
1739 Mandeville Road,
Florence, SC, 29501-7026, US
3.07 mi from Florence, SC
3.4 stars rating. 202 reviews3.4 stars rating. 202 reviews
Sold outfor your selected dates
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Park Inn by Radisson Florence, SC
1729 Mandeville Road,
Florence, SC, 29501, US
3.06 mi from Florence, SC
4.3 stars rating. 264 reviews4.3 stars rating. 264 reviews
Sold outfor your selected dates
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Quality Inn Laurinburg
14 Jameson Inn Ct,
Laurinburg, NC, 28352, US
42.08 mi from Florence, SC
3.8 stars rating. 502 reviews3.8 stars rating. 502 reviews
Sold outfor your selected dates
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Palmetto Inn
6137 Alex Harvin Hwy,
Manning, SC, 29102, US
48.19 mi from Florence, SC
No Reviews YetNo Reviews Yet
Coming soonStart booking Aug 02, 2025
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Good to know

Extended stay hotels

2 of 27 hotels in Florence

Highest Price

$148

Lowest Price

$43

Avg. rating

3.4 (20201 reviews)

Weekly Rate

$301

Monthly Rate

22 Extended Stay hotels near Florence, SC

Suburban Studios Florence - Darlington

MainStay Suites

Below are additional hotels in the area that do not match your exact search criteria.

Econo Lodge

Sleep Inn Florence North

Comfort Suites Florence I-95

Comfort Inn & Suites

Quality Inn & Suites Florence Civic Center

Quality Inn

Quality Inn Mullins - Marion

Quality Inn & Suites

Econo Lodge Cheraw Market Street

Quality Inn Bennettsville

Quality Inn Cheraw

Quality Inn

Quality Inn Manning I-95

Quality Inn

Econo Lodge

Sleep Inn

Quality Inn Conway Northwest

Comfort Inn

Comfort Inn & Suites

Comfort Suites

Change your dates to book properties below.

Clarion Inn & Suites

Country Inn & Suites by Radisson, Florence, SC

Park Inn by Radisson Florence, SC

Quality Inn Laurinburg

Palmetto Inn

Other Florence searches

Good to know

2 of 27 hotels in Florence

$148

$43

3.4 (20201 reviews)

$301

$1,290