Book Sleep Hotels in Roxana, IL

Sleep Inn O'Fallon near I-64
140 Venita Drive,
O Fallon, IL, 62269, US
18.69 mi from Roxana, IL, US
3.37 stars rating. Good. 1348 reviews
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Strikethrough Rate:~~$84~~Discounted rate:$78USD/night
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Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
24.74 mi from Roxana, IL, US
3.08 stars rating. Fair. 1047 reviews
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Strikethrough Rate:~~$98~~Discounted rate:$91USD/night
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Below are additional hotels in the area that do not match your exact search criteria.

Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
5.47 mi from Roxana, IL, US
3.65 stars rating. Good. 865 reviews
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Strikethrough Rate:~~$134~~Discounted rate:$121USD/night
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Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
6.38 mi from Roxana, IL, US
4.16 stars rating. Very Good. 1379 reviews
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Strikethrough Rate:~~$174~~Discounted rate:$157USD/night
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Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
11.53 mi from Roxana, IL, US
4.2 stars rating. Excellent. 1970 reviews
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Strikethrough Rate:~~$154~~Discounted rate:$139USD/night
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Econo Lodge Inn & Suites Granite City - St. Louis
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
6.69 mi from Roxana, IL, US
3.44 stars rating. Good. 391 reviews
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Strikethrough Rate:~~$78~~Discounted rate:$73USD/night
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Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
16.56 mi from Roxana, IL, US
4.1 stars rating. Very Good. 1999 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$92USD/night
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Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
17.34 mi from Roxana, IL, US
3.45 stars rating. Good. 1815 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$89USD/night
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
15.6 mi from Roxana, IL, US
3.41 stars rating. Good. 1477 reviews
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Strikethrough Rate:~~$86~~Discounted rate:$80USD/night
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Quality Inn O'Fallon IL - St. Louis
1409 W US 50,
O Fallon, IL, 62269, US
18.54 mi from Roxana, IL, US
3.55 stars rating. Good. 946 reviews
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Strikethrough Rate:~~$71~~Discounted rate:$67USD/night
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Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
17.36 mi from Roxana, IL, US
3.16 stars rating. Good. 234 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$89USD/night
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Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
16.24 mi from Roxana, IL, US
2.71 stars rating. Fair. 716 reviews
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Strikethrough Rate:~~$74~~Discounted rate:$69USD/night
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Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
17.73 mi from Roxana, IL, US
3.26 stars rating. Good. 3067 reviews
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Strikethrough Rate:~~$94~~Discounted rate:$87USD/night
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AWARD WINNER
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
27.52 mi from Roxana, IL, US
4.73 stars rating. Exceptional. 2018 reviews
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Strikethrough Rate:~~$179~~Discounted rate:$166USD/night
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
19.6 mi from Roxana, IL, US
4.06 stars rating. Very Good. 185 reviews
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Strikethrough Rate:~~$134~~Discounted rate:$125USD/night
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Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
17.42 mi from Roxana, IL, US
3.76 stars rating. Good. 322 reviews
BOOK NOW AND SAVE 12%
Strikethrough Rate:~~$75~~Discounted rate:$66USD/night
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
27.29 mi from Roxana, IL, US
4.05 stars rating. Very Good. 231 reviews
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Strikethrough Rate:~~$140~~Discounted rate:$130USD/night
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Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
17.29 mi from Roxana, IL, US
3.55 stars rating. Good. 206 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$104USD/night
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AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
23.44 mi from Roxana, IL, US
4.64 stars rating. Exceptional. 671 reviews
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Strikethrough Rate:~~$214~~Discounted rate:$199USD/night
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Comfort Inn & Suites Saint Louis Lafayette Square
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
18.22 mi from Roxana, IL, US
3.78 stars rating. Good. 124 reviews
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Strikethrough Rate:~~$219~~Discounted rate:$204USD/night
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Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
20.88 mi from Roxana, IL, US
3.53 stars rating. Good. 1354 reviews
BOOK NOW AND SAVE 16%
Strikethrough Rate:~~$97~~Discounted rate:$81USD/night
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Comfort Inn & Suites OFallon - St Louis Area
116 Regency Park,
O'Fallon, IL, 62269, US
18.89 mi from Roxana, IL, US
2.32 stars rating. Fair. 124 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$94~~Discounted rate:$85USD/night
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
23.82 mi from Roxana, IL, US
4.02 stars rating. Very Good. 2094 reviews
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Strikethrough Rate:~~$159~~Discounted rate:$148USD/night
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MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
19.59 mi from Roxana, IL, US
3.92 stars rating. Good. 242 reviews
BOOK NOW AND SAVE 16%
Strikethrough Rate:~~$134~~Discounted rate:$112USD/night
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
23.57 mi from Roxana, IL, US
No Reviews Yet
BOOK NOW AND SAVE 14%
Strikethrough Rate:~~$185~~Discounted rate:$160USD/night
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Fees included
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MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
21.17 mi from Roxana, IL, US
3.17 stars rating. Good. 201 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$101USD/night
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NEW TO CHOICE
Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
16.36 mi from Roxana, IL, US
1.42 stars rating. Fair. 84 reviews
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Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
23.03 mi from Roxana, IL, US
3.55 stars rating. Good. 3113 reviews
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The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
5.49 mi from Roxana, IL, US
2.94 stars rating. Fair. 108 reviews
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
24.33 mi from Roxana, IL, US
No Reviews Yet
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Roxana hotels by brand

Ascend Hotels

Comfort Inn Hotels

Comfort Suites Hotels

Country Inn Suites Hotels

Good to know

Number of hotels

26 of 30 hotels in Roxana

Highest Price

$204

Lowest Price

$66

Avg. rating

2 hotels near Roxana, IL, US match your filters

Sleep Inn O'Fallon near I-64

Sleep Inn Saint Charles North

Below are additional hotels in the area that do not match your exact search criteria.

Comfort Inn Alton near I-255

Comfort Inn Edwardsville - St. Louis

Comfort Inn Collinsville near St. Louis

Econo Lodge Inn & Suites Granite City - St. Louis

Comfort Inn & Suites Hazelwood - St. Louis

Comfort Suites Fairview Heights - St Louis

Quality Inn Florissant-St. Louis

Quality Inn O'Fallon IL - St. Louis

Country Inn & Suites by Radisson, Fairview Heights, IL

Quality Inn & Suites Caseyville - St. Louis

Quality Inn Saint Louis Airport

Comfort Suites St. Louis - Sunset Hills

Comfort Inn St. Louis Airport

Econo Lodge Inn & Suites Fairview Heights - St. Louis

Country Inn & Suites by Radisson, St. Peters, MO

Radisson Hotel Fairview Heights - St. Louis

Country Inn & Suites by Radisson, St. Charles Historic District

Comfort Inn & Suites Saint Louis Lafayette Square

Quality Inn & Suites near St. Louis and I-255

Comfort Inn & Suites OFallon - St Louis Area

Comfort Suites St Charles-St Louis

MainStay Suites St. Louis Airport

Hollywood Casino St Louis

MainStay Suites St. Louis - Galleria

Change your dates to book properties below.

Radisson Hotel St. Louis Downtown Convention Center

Comfort Inn St. Louis - Westport Event Center

The Great Rivers, an Ascend Collection Hotel

River City Casino & Hotel

Other Roxana searches

Roxana hotels by brand

Good to know

26 of 30 hotels in Roxana

$204

$66

3.3 (28331 reviews)