Book Quality Hotels in Florence, SC

Quality Inn & Suites Florence Civic Center
150 Dunbarton Drive,
Florence, SC, 29501, US
4.24 mi from Florence, SC
3.94 stars rating. Good. 1752 reviews3.94 stars rating. Good. 1752 reviews
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Strikethrough Rate:~~$100~~Discounted rate:$93USD/night
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Quality Inn
903 South Fifth Street,
Hartsville, SC, 29550, US
20.62 mi from Florence, SC
2.96 stars rating. Fair. 397 reviews2.96 stars rating. Fair. 397 reviews
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Strikethrough Rate:~~$78~~Discounted rate:$73USD/night
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Quality Inn & Suites
202 North Ron McNair Blvd.,
Lake City, SC, 29560, US
22.06 mi from Florence, SC
3.36 stars rating. Good. 100 reviews3.36 stars rating. Good. 100 reviews
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Strikethrough Rate:~~$135~~Discounted rate:$126USD/night
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Below are additional hotels in the area that do not match your exact search criteria.

Comfort Inn & Suites
527 Woody Jones Blvd.,
Florence, SC, 29501, US
3.9 mi from Florence, SC
4.49 stars rating. Excellent. 1201 reviews4.49 stars rating. Excellent. 1201 reviews
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Strikethrough Rate:~~$112~~Discounted rate:$106USD/night
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Comfort Suites Florence I-95
2120 West Lucas Street,
Florence, SC, 29501, US
3.32 mi from Florence, SC
4.26 stars rating. Excellent. 2636 reviews4.26 stars rating. Excellent. 2636 reviews
$104USD/night
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Clarion Inn & Suites
1819 West Lucas Street, Building A,
Florence, SC, 29501, US
2.75 mi from Florence, SC
1.93 stars rating. Fair. 196 reviews1.93 stars rating. Fair. 196 reviews
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Strikethrough Rate:~~$62~~Discounted rate:$59USD/night
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Sleep Inn Florence North
1833 Florence Park Dr., I-95 & US 52,
Florence, SC, 29501, US
3.31 mi from Florence, SC
3.74 stars rating. Good. 1983 reviews3.74 stars rating. Good. 1983 reviews
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Strikethrough Rate:~~$80~~Discounted rate:$74USD/night
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Suburban Studios Florence I-95
1914 West Lucas Street, I-95 & US 52,
Florence, SC, 29501, US
2.84 mi from Florence, SC
2.92 stars rating. Fair. 1327 reviews2.92 stars rating. Fair. 1327 reviews
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Strikethrough Rate:~~$55~~Discounted rate:$51USD/night
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Park Inn by Radisson Florence, SC
1729 Mandeville Road,
Florence, SC, 29501, US
3.06 mi from Florence, SC
4.27 stars rating. Excellent. 362 reviews4.27 stars rating. Excellent. 362 reviews
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Strikethrough Rate:~~$94~~Discounted rate:$89USD/night
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Econo Lodge
1920 West Lucas Street,
Florence, SC, 29501, US
2.86 mi from Florence, SC
2.86 stars rating. Fair. 1362 reviews2.86 stars rating. Fair. 1362 reviews
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Strikethrough Rate:~~$58~~Discounted rate:$51USD/night
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MainStay Suites
1819 West Lucas Street, Building B,
Florence, SC, 29501, US
2.79 mi from Florence, SC
1.92 stars rating. Fair. 63 reviews1.92 stars rating. Fair. 63 reviews
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Strikethrough Rate:~~$72~~Discounted rate:$67USD/night
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Rodeway Inn
415 S. Irby St.,
Florence, SC, 29501, US
0.46 mi from Florence, SC
No Reviews YetNo Reviews Yet
Coming soonStart booking Sep 30, 2025
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Good to know

Number of hotels

3 of 12 hotels in Florence

Highest Price

$126

Lowest Price

$51

Avg. rating

3 hotels near Florence, SC match your filters

Quality Inn & Suites Florence Civic Center

Quality Inn

Quality Inn & Suites

Below are additional hotels in the area that do not match your exact search criteria.

Comfort Inn & Suites

Comfort Suites Florence I-95

Clarion Inn & Suites

Sleep Inn Florence North

Suburban Studios Florence I-95

Park Inn by Radisson Florence, SC

Econo Lodge

MainStay Suites

Change your dates to book properties below.

Rodeway Inn

Other Florence searches

Good to know

3 of 12 hotels in Florence

$126

$51

3.1 (11379 reviews)