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    • Econo Lodge

      9112 Old Number 6 Hwy, Santee, SC, 29142, US
      3.0Fair(155)
      Hotel Amenities:
      Free WiFi
      Pet Friendly
      Truck Parking
      Book Now & Save 7%
      FromOriginal rate:$75Discounted rate:$70USDPer Night
      $78 USD Total
      See Availability

    • Econo Lodge

      5971 West Jim Bilton Blvd., Saint George, SC, 29477, US
      3.1Good(319)
      Hotel Amenities:
      Free WiFi
      Outdoor Pool
      Pet Friendly
      Truck Parking
      Book Now & Save 7%
      FromOriginal rate:$59Discounted rate:$55USDPer Night
      $61 USD Total
      See Availability
      • Below are additional hotels in the area that do not match your exact search criteria.

    • Comfort Inn & Suites Santee I-95

      221 Britain Street, Santee, SC, 29142, US
      3.9Good(1,532)
      Hotel Amenities:
      Free WiFi
      Free Continental Breakfast
      Free Hot Breakfast
      Outdoor Pool
      Fitness Center
      Book Now & Save 7%
      FromOriginal rate:$119Discounted rate:$111USDPer Night
      $123 USD Total
      See Availability

    • Quality Inn & Suites

      8929 Old Number Six Highway, Santee, SC, 29142, US
      2.7Fair(122)
      Hotel Amenities:
      Free WiFi
      Free Continental Breakfast
      Free Hot Breakfast
      Pet Friendly
      Fitness Center
      Book Now & Save 7%
      FromOriginal rate:$74Discounted rate:$69USDPer Night
      $77 USD Total
      See Availability

    • Rodeway Inn Santee I-95

      123 Mall St., Santee, SC, 29142, US
      2.6Fair(250)
      Hotel Amenities:
      Free WiFi
      Pet Friendly
      Restaurant
      Fitness Center
      Business Center
      Book Now & Save 7%
      FromOriginal rate:$90Discounted rate:$84USDPer Night
      $93 USD Total
      See Availability

    • Suburban Studios

      3671 Saint Matthews Road, Building B, Orangeburg, SC, 29118, US
      4.7Exceptional(15)
      Hotel Amenities:
      Free WiFi
      Pet Friendly
      Kitchen
      Book Now & Save 7%
      FromOriginal rate:$73Discounted rate:$68USDPer Night
      $75 USD Total
      See Availability

    • Quality Inn & Suites

      3671 Saint Matthews Road, Building A, Orangeburg, SC, 29118, US
      3.3Good(1,445)
      Hotel Amenities:
      Free WiFi
      Free Continental Breakfast
      Free Hot Breakfast
      Outdoor Pool
      Pet Friendly
      Book Now & Save 5%
      FromOriginal rate:$62Discounted rate:$59USDPer Night
      $65 USD Total
      See Availability

    • Sleep Inn

      3689 St. Matthews Rd, Orangeburg, SC, 29118, US
      3.9Good(1,099)
      Hotel Amenities:
      Free WiFi
      Free Continental Breakfast
      Free Hot Breakfast
      Smoke Free
      Outdoor Pool
      Book Now & Save 16%
      FromOriginal rate:$102Discounted rate:$85USDPer Night
      $101 USD Total
      See Availability

    • Comfort Inn & Suites

      746 Citadel Road, Orangeburg, SC, 29118, US
      3.9Good(1,414)
      Hotel Amenities:
      Free WiFi
      Free Continental Breakfast
      Free Hot Breakfast
      Smoke Free
      Fitness Center
      Book Now & Save 7%
      FromOriginal rate:$119Discounted rate:$111USDPer Night
      $123 USD Total
      See Availability

    • Quality Inn Manning I-95

      3031 Paxville Highway, Manning, SC, 29102, US
      3.6Good(32)
      Hotel Amenities:
      Free WiFi
      Free Continental Breakfast
      Free Hot Breakfast
      Smoke Free
      Outdoor Pool
      Book Now & Save 7%
      FromOriginal rate:$75Discounted rate:$70USDPer Night
      $78 USD Total
      See Availability

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    Santee hotels information

    • Number of hotels in Santee
      10
    • Highest Price
      $111
    • Lowest Price
      $55
    • Number of reviews
      6383
    • Avg. rating
      3.5