Book Top Rated Hotels in Odessa, TX | Choice Hotels

Comfort Inn & Suites, Odessa I-20
801 South JBS Parkway,
Odessa, TX, 79761, US
3.04 mi from Odessa, TX, USA
3.79 stars rating. Good. 662 reviews3.79 stars rating. Good. 662 reviews
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Strikethrough Rate:~~$145~~Discounted rate:$131USD/night
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MainStay Suites Odessa I-20
1801 S. Highway 385,
Odessa, TX, 79766, US
1.55 mi from Odessa, TX, USA
4.43 stars rating. Excellent. 213 reviews4.43 stars rating. Excellent. 213 reviews
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Strikethrough Rate:~~$139~~Discounted rate:$135USD/night
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Sleep Inn & Suites Odessa near University
3101 East Business 20,
Odessa, TX, 79761, US
3.48 mi from Odessa, TX, USA
3.96 stars rating. Good. 364 reviews3.96 stars rating. Good. 364 reviews
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Strikethrough Rate:~~$135~~Discounted rate:$122USD/night
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Comfort Suites Odessa near University
4801 East 50th Street,
Odessa, TX, 79762, US
4.16 mi from Odessa, TX, USA
3.88 stars rating. Good. 676 reviews3.88 stars rating. Good. 676 reviews
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Strikethrough Rate:~~$165~~Discounted rate:$149USD/night
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AWARD WINNER
Suburban Studios Midland I-20
3001 Antelope Trail,
Midland, TX, 79706, US
15.02 mi from Odessa, TX, USA
4.41 stars rating. Excellent. 193 reviews4.41 stars rating. Excellent. 193 reviews
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Strikethrough Rate:~~$210~~Discounted rate:$200USD/night
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AWARD WINNER
Sleep Inn & Suites Midland West
5612 Deauville Blvd,
Midland, TX, 79706, US
15.98 mi from Odessa, TX, USA
4.41 stars rating. Excellent. 705 reviews4.41 stars rating. Excellent. 705 reviews
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Strikethrough Rate:~~$209~~Discounted rate:$188USD/night
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Comfort Suites Midland West
5606 Westridge Blvd,
Midland, TX, 79706, US
16.13 mi from Odessa, TX, USA
4.26 stars rating. Excellent. 399 reviews4.26 stars rating. Excellent. 399 reviews
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Strikethrough Rate:~~$259~~Discounted rate:$233USD/night
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Quality Suites Midland North Loop 250
4706 North Garfield Street,
Midland, TX, 79705, US
20.1 mi from Odessa, TX, USA
4 stars rating. Very Good. 642 reviews4 stars rating. Very Good. 642 reviews
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Strikethrough Rate:~~$179~~Discounted rate:$161USD/night
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Comfort Inn Midland South I-20
910 West I-20,
Midland, TX, 79701, US
19.1 mi from Odessa, TX, USA
3.69 stars rating. Good. 594 reviews3.69 stars rating. Good. 594 reviews
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Strikethrough Rate:~~$159~~Discounted rate:$143USD/night
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MainStay Suites Midland
2500 South Lamesa Road,
Midland, TX, 79701, US
20.3 mi from Odessa, TX, USA
3.71 stars rating. Good. 188 reviews3.71 stars rating. Good. 188 reviews
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Strikethrough Rate:~~$139~~Discounted rate:$129USD/night
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Rodeway Inn Midland South
1000 S Midkiff Rd,
Midland, TX, 79701-7132, US
17.56 mi from Odessa, TX, USA
1.35 stars rating. Fair. 17 reviews1.35 stars rating. Fair. 17 reviews
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Strikethrough Rate:~~$65~~Discounted rate:$57USD/night
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NEW TO CHOICE
Quality Inn
3071 E Business 20,
Odessa, TX, 79761, US
3.37 mi from Odessa, TX, USA
No Reviews YetNo Reviews Yet
Coming soonStart booking Feb 02, 2026
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Quality Inn Midland South
902 Interstate 20 West,
Midland, TX, 79701, US
19.21 mi from Odessa, TX, USA
3.89 stars rating. Good. 598 reviews3.89 stars rating. Good. 598 reviews
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Good to know

Top-Rated hotels

13 hotels in Odessa

Highest Price

$233

Lowest Price

$57

Avg. rating

3.5 (5251 reviews)